October 19, 2020
Presenter: Cathal J. Kearney, PhD
University of Massachusetts Amherst
Topic: "Controlling the Timing of Therapeutic Delivery to Enhance Regenerative Medicine Strategies"
Time: 1:45 pm - 2:45 pm
Session Number: 120 216 7144
Dr. Kearney received his Ph.D. in 2011 from Massachusetts Institute of Technology’s Harvard/MIT Division of Health Sciences and Technology programme. Engineering tools to understand and mimic natural cue timing motivates the central research themes in his laboratory: the precise temporal control of local therapeutic delivery; the effect of therapeutic delivery timing on efficacy; and integrating these platforms within biomaterials. By developing technologies to deliver therapeutics at specific time-points, his research aims to probe the role of timing in repair processes and to ultimately drive coordination of biological processes. Designing novel tissue engineering scaffolds and integrating these delivery systems in them is a key parallel focus in the lab.
Dr. Kearney co-developed an on-demand ultrasound-responsive drug delivery system that is capable of delivering a range of therapeutics at precise timepoints in vitro and in vivo. His lab was the first to produce a porous tissue engineering scaffold using matrix grown by induced pluripotent stem (iPS) cells. His team has also customized tissue engineering scaffolds with drug delivery and other functionalities for several applications. Dr. Kearney has co-authored over 30 peer-reviewed journal articles and is a co-inventor on 3 patents or patent applications.