Dr. Carlos E. Palant graduated from the University of Buenos Aires, Faculty of Medicine in 1975 with an Honors Diploma. He trained as an Internal Medicine Resident at the Italian Hospital of Buenos Aires and at the Barzilai Medical Center in Ashkelon, Israel. In 1980, he moved to Buffalo, NY, to complete a Fellowship in Nephrology. After completing the two-year requirement in Clinical Nephrology, he remained at SUNY Buffalo in the Nephrology Division as a Research Assistant Professor. Under the mentorship of Professor Carl J. Bentzel, Dr. Palant investigated the role of intracellular calcium in the regulation of tight junction permeability in the Necturus gallbladder. Using intracellular calcium-sensitive microelectrodes he was able to demonstrate that tight junctional permeability is, in part, modulated by varying concentrations in intracellular calcium.
After completing this research at SUNY Buffalo, Dr. Palant continued his investigations at the Sepulveda VA Medical Center in California working on calcium-mediated regulation of the electrophysiology of leaky epithelia. In 1987, Dr. Palant was appointed as Chief of Home Hemodialysis at the Brooklyn VAMC and promoted to Associate Professor of Medicine at SUNY Downstate in 1993. In Brooklyn, he learned cell culture of glomerular mesangial cells, and studied their electrophysiological properties using conventional, ion-sensitive and patch-clamp microelectrodes. Working in collaboration with Dr. William Craelius, his team described several stretch-sensitive ion channels in mesangial cells. In 1994, Dr. Palant became the Chief, Nephrology Division, at the University of Nevada, Reno, where he actively pursued the expansion of dialysis services in underserved regions of the State of Nevada. In the year 2000, Dr. Palant became the Chief of Nephrology at the Washington D.C. VAMC where he served until December of 2017. He was appointed as Professor of Medicine at The George Washington University School of Medicine in 2015 and as Clinical Professor of Medicine at the Uniformed Services University in 2018.
Dr. Palant’s current research interests focus on the role of acute kidney injury in the development of chronic kidney disease and the use of bedside equations and epidemiological studies to predict adverse late effects of acute kidney injury. During his career, Dr. Palant received the New York Kidney Disease Institute Fellowship Award, the Charles E. Culpeper Foundation Fellowship Award, and a Dept. of Veterans Affairs Career Development Award. His research has been funded by the Dept. of Veterans Affairs Merit Review Board, and private sources. He is a co-investigator in NIH-funded projects as well. Dr. Palant is a graduate of the American Boards of Internal Medicine and Nephrology.